| Disease category | Percent of all YPLLs lost, worldwide | Percent of all DALYs lost, worldwide | Percent of all YPLLs lost, Europe | Percent of all DALYs lost, Europe | Percent of all YPLLs lost, US and Canada | Percent of all DALYs lost, US and Canada | 
| Infectious and parasitic diseases, especially lower respiratory tract infections, diarrhea, AIDS, tuberculosis, and malaria | 37% | 26% | 9% | 6% | 5% | 3% | 
| Neuropsychiatric conditions, e.g. depression | 2% | 13% | 3% | 19% | 5% | 28% | 
| Injuries, especially motor vehicle accidents | 14% | 12% | 18% | 13% | 18% | 10% | 
| Cardiovascular diseases, principally heart attacks and stroke | 14% | 10% | 35% | 23% | 26% | 14% | 
| Premature birth and other perinatal deaths | 11% | 8% | 4% | 2% | 3% | 2% | 
| Cancer | 8% | 5% | 19% | 11% | 25% | 13% |