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Found 2 translations.
Name | Current message text |
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h English (en) | Vitamin B<sub>12</sub> deficiencies have a greater effect on the pregnant, young children, and elderly people, and are more common in middle and lower developed countries due to malnutrition. The most common cause of vitamin B<sub>12</sub> deficiency in developed countries is [[malabsorption|impaired absorption]] due to a loss of [[Intrinsic factor|gastric intrinsic factor]] (IF) which must be bound to a food-source of B<sub>12</sub> in order for absorption to occur. A second major cause is an age-related decline in [[Gastric acid|stomach acid]] production ([[achlorhydria]]), because acid exposure frees protein-bound vitamin. For the same reason, people on long-term antacid therapy, using [[proton-pump inhibitors]], [[H2 blocker|H<sub>2</sub> blockers]] or other antacids are at increased risk. |
h Japanese (ja) | ビタミンB<sub>12</sub>欠乏は、妊娠中、幼児、高齢者に大きな影響を及ぼし、栄養失調のために中低開発国でより一般的である。先進国におけるビタミンB<sub>12</sub>欠乏の最も一般的な原因は、吸収が起こるためには食物由来のB<sub>12</sub>と結合していなければならない[[Intrinsic factor/ja|胃内在因子]](IF)の損失による[[malabsorption/ja|吸収障害]]である。第二の主な原因は、加齢に伴う[[gastric acid/ja|胃酸]]産生の低下である([[archlorhydria/ja|無胃酸症]])。同じ理由で、[[proton-pump inhibitors/ja|プロトンポンプ阻害薬]]や[[H2 blocker/ja|H<sub>2</sub>遮断薬]]などの制酸剤を長期間使用している人はリスクが高くなる。 |