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NameCurrent message text
 h English (en)==Definition==
Protein toxicity occurs when protein [[metabolic wastes]] build up in the body. During protein metabolism, nitrogenous wastes such as urea, uric acid, ammonia, and creatinine are produced. These compounds are not utilized by the human body and are usually excreted by the kidney. However, due to conditions such as renal insufficiency, the under-functioning kidney is unable to excrete these metabolic wastes, causing them to accumulate in the body and lead to toxicity. Although there are many causes of protein toxicity, this condition is most prevalent in people with [[chronic kidney disease]] who consumes a protein-rich diet, specifically, proteins from animal sources that are rapidly digested and metabolized, causing the release of a high concentration of protein metabolic wastes in the blood stream rapidly.
 h Japanese (ja)==定義==
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タンパク質中毒は、タンパク質の[[metabolic wastes/ja|代謝老廃物]]が体内に蓄積することで起こる。タンパク質の代謝中に、尿素、尿酸、アンモニア、クレアチニンなどの窒素性老廃物が産生される。これらの化合物は人体では利用されず、通常は腎臓から排泄される。しかし、腎不全などの状態により、機能低下した腎臓はこれらの代謝老廃物を排泄することができず、体内に蓄積して毒性を引き起こす。タンパク質中毒の原因はたくさんあるが、この状態は、タンパク質が豊富な食事、具体的には、消化・代謝が速い動物性由来のタンパク質を摂取している[[chronic kidney disease/ja|慢性腎臓病]]の人に最も多く、血液中に高濃度のタンパク質代謝老廃物が急速に放出される。