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Found 2 translations.

Name	Current message text
^h English (en)	=== Pharmacokinetics === Metformin has an oral [[bioavailability]] of 50–60% under [[fasting]] conditions, and is absorbed slowly. Peak plasma concentrations (C<sub>max</sub>) are reached within 1–3 hours of taking immediate-release metformin and 4–8 hours with extended-release formulations. The [[plasma protein binding]] of metformin is negligible, as reflected by its very high [[volume of distribution\|apparent volume of distribution]] (300–1000 L after a single dose). [[Steady state]] is usually reached in 1–2 days.
^h Japanese (ja)	=== 薬物動態 === メトホルミンの経口[[bioavailability/ja\|生物学的利用能]]は、[[fasting/ja\|空腹]]条件下で50～60％であり、ゆっくりと吸収される。血漿中濃度のピーク（C<sub>max</sub>）は、メトホルミンの即時放出型製剤では服用後1～3時間以内に、徐放型製剤では4～8時間以内に到達する。メトホルミンの[[plasma protein binding/ja\|血漿タンパク質結合]]は、非常に高い[[volume of distributino/ja\|見かけの分布容積]]（単回投与で300～1000 L）に反映されるように、無視できる。[[Steady state/ja\|定常状態]]は通常1～2日で到達する。