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Found 2 translations.

Name	Current message text
^h English (en)	=== Mechanism of action === The molecular mechanism of metformin is not completely understood. Multiple potential mechanisms of action have been proposed: inhibition of the mitochondrial respiratory chain ([[Respiratory complex I\|complex I]]), activation of [[AMP-activated protein kinase]] (AMPK), inhibition of glucagon-induced elevation of [[cyclic adenosine monophosphate]] (cAMP) with reduced activation of [[protein kinase A]] (PKA), complex IV–mediated inhibition of the GPD2 variant of mitochondrial [[Glycerol-3-phosphate dehydrogenase#GPD2\|glycerol-3-phosphate dehydrogenase]] (thereby reducing glycerol-derived hepatic gluconeogenesis), and an effect on [[gut flora\|gut microbiota]].
^h Japanese (ja)	=== 作用機序 === メトホルミンの分子メカニズムは完全には解明されていない。複数の潜在的な作用機序が提唱されている：ミトコンドリア呼吸鎖（[[Respiratory complex I/ja\|複合体I]]）の阻害、[[AMP-activated protein kinase/ja\|AMP活性化プロテインキナーゼ]]（AMPK）の活性化、[[protein kinase A/ja\|プロテインキナーゼA]]（PKA）の活性化の減少を伴うグルカゴン誘導性の[[gut flora\|gut microbiota/ja\|環状アデノシン一リン酸]]（cAMP）の上昇の阻害、ミトコンドリア[[Glycerol-3-phosphate dehydrogenase/ja#GPD2\|グリセロール-3-リン酸デヒドロゲナーゼ]]のGPD2変異体の複合体IV媒介阻害（それにより、グリセロール由来の肝グルコネシン生成を減少させる）、および[[gut flora/ja\|腸内細菌叢]]への影響。