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 h English (en)[[Low-density lipoprotein]] (LDL) particles in blood plasma invade the [[endothelium]] and become oxidized, creating risk of [[cardiovascular disease]]. A complex set of biochemical reactions regulates the oxidation of [[Low-density lipoprotein|LDL]], involving enzymes (such as [[Lp-LpA2]]) and [[free radical]]s in the endothelium.
 h Japanese (ja)血漿中の[[Low-density lipoprotein/ja|低比重リポ蛋白]](LDL)粒子が[[endothelium/ja|内皮]]に侵入して酸化されると、[[cardiovascular disease/ja|心血管疾患]]のリスクが生じる。複雑な一連の生化学反応が[[Low-density lipoprotein/ja|LDL]]の酸化を制御しており、酵素([[Lp-LpA2/ja|Lp-LpA2]]など)と内皮の[[free radical/ja|フリーラジカル]]が関与している。