Antidiarrheal/en: Difference between revisions

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* [[Opioid]]s' classical use besides pain relief is as an anti-diarrhoeal drug. Opioids have [[agonist]] actions on the intestinal opioid receptors, which when activated cause [[constipation]]. Drugs such as [[morphine]] or [[codeine]] can be used to relieve diarrhoea this way. A notable opioid for the purpose of relief of diarrhoea is [[loperamide]] which is only an agonist of the [[mu Opioid receptor|μ opioid receptor]]s in the large intestine and does not have opioid affects in the [[central nervous system]] as it doesn't cross the [[blood–brain barrier]] in significant amounts. This enables loperamide to be used to the same benefit as other opioid drugs but without the CNS side effects or potential for abuse.

*[[Octreotide]] (somatostatin analogue) may be used in hospitalized patients to treat secretory diarrhea.

* [[~~Probiotics~~]] are ~~commonly given to breastfeeding mothers and their young children to prevent eczema (~~[[~~dermatitis~~]]), ~~but~~ no ~~good evidence shows efficacy~~ for ~~this purpose. There~~ is ~~little~~ evidence ~~to support~~ the ~~use of probiotics to treat [[atopic dermatitis]], and some risk~~ of ~~[[adverse effect]]s~~.

* Some [[probiotics]] are suggested as a possible treatment for various forms of [[gastroenteritis]]. As a treatment for infectious diarrhea, probiotics are of no benefit to people who have the condition for more than two days, and there is no evidence they lessen the duration of diarrhea overall.

==See also==

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 * [[Opioid]]s' classical use besides pain relief is as an anti-diarrhoeal drug. Opioids have [[agonist]] actions on the intestinal opioid receptors, which when activated cause [[constipation]]. Drugs such as [[morphine]] or [[codeine]] can be used to relieve diarrhoea this way. A notable opioid for the purpose of relief of diarrhoea is [[loperamide]] which is only an agonist of the [[mu Opioid receptor|μ opioid receptor]]s in the large intestine and does not have opioid affects in the [[central nervous system]] as it doesn't cross the [[blood–brain barrier]] in significant amounts. This enables loperamide to be used to the same benefit as other opioid drugs but without the CNS side effects or potential for abuse.
 *[[Octreotide]] (somatostatin analogue) may be used in hospitalized patients to treat secretory diarrhea.
-* [[Probiotics]] are commonly given to breastfeeding mothers and their young children to prevent eczema ([[dermatitis]]), but no good evidence shows efficacy for this purpose. There is little evidence to support the use of probiotics to treat [[atopic dermatitis]], and some risk of [[adverse effect]]s.
+* Some [[probiotics]] are suggested as a possible treatment for various forms of [[gastroenteritis]]. As a treatment for infectious diarrhea, probiotics are of no benefit to people who have the condition for more than two days, and there is no evidence they lessen the duration of diarrhea overall.
 ==See also==