Translations:Collagen/20/en: Difference between revisions

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Message definition (Collagen)
===Amino acids===
Collagen has an unusual [[amino acid]] composition and sequence:
* [[Glycine]] is found at almost every third [[residue (biochemistry)|residue]].
* [[Proline]] makes up about 17% of collagen.
* Collagen contains two unusual derivative amino acids not directly inserted during [[translation (genetics)|translation]]. These amino acids are found at specific locations relative to glycine and are modified post-translationally by different enzymes, both of which require [[vitamin C]] as a [[cofactor (biochemistry)|cofactor]].
** [[Hydroxyproline]] derived from proline
** [[Hydroxylysine]] derived from [[lysine]] – depending on the type of collagen, varying numbers of hydroxylysines are [[glycosylation|glycosylated]] (mostly having [[disaccharide]]s attached).

Amino acids

Collagen has an unusual amino acid composition and sequence:

  • Glycine is found at almost every third residue.
  • Proline makes up about 17% of collagen.
  • Collagen contains two unusual derivative amino acids not directly inserted during translation. These amino acids are found at specific locations relative to glycine and are modified post-translationally by different enzymes, both of which require vitamin C as a cofactor.
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