Antidiarrheal/en: Difference between revisions
Antidiarrheal/en
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{{Short description|Medicine to treat diarrhea}} | {{Short description|Medicine to treat diarrhea}} | ||
{| class="wikitable sortable" style="width:100%" | |||
|+止瀉薬 | |||
|- | |||
!一般名 | |||
!先発名 | |||
!class="unsortable"| 日本 | |||
!創薬/開発 | |||
!備考 | |||
|- | |||
|ラクトミン([[Enterococcus faecium/ja]])<br />酪酸菌([[Clostridium butyricum/ja]])<br />糖化菌([[Bacillus subtilis/ja]]) | |||
|[https://www.torii.co.jp/iyakuDB/medical_info/bio_t.html ビオスリー] ([https://www.torii.co.jp/iyakuDB/data/pi/bio.pdf PI]) ([https://www.torii.co.jp/iyakuDB/data/if/if_bio.pdf IF]) | |||
|販売 | |||
|[[鳥居薬品]] | |||
| | |||
|- | |||
|ビフィズス菌([[Bifidobacterium/ja]]) | |||
|[https://medical.kowa.co.jp/product/item-43.html ラックビー] ([https://pins.japic.or.jp/pdf/newPINS/00060088.pdf PI]) ([https://medical.kowa.co.jp/asset/item/43/1-pi_119.pdf IF]) | |||
|販売 | |||
|[[Kowa (company)|興和]] | |||
| | |||
|- | |||
|} | |||
{{Pathnav|medication|frame=1}} | |||
{{wiktionary|Antidiarrheal}} | {{wiktionary|Antidiarrheal}} | ||
An '''anti-diarrheal drug''' (or '''anti-diarrhoeal drug''' in British English) is any [[medication]] which provides symptomatic relief for [[diarrhea]]. | An '''anti-diarrheal drug''' (or '''anti-diarrhoeal drug''' in British English) is any [[medication]] which provides symptomatic relief for [[diarrhea]]. | ||
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* [[Opioid]]s' classical use besides pain relief is as an anti-diarrhoeal drug. Opioids have [[agonist]] actions on the intestinal opioid receptors, which when activated cause [[constipation]]. Drugs such as [[morphine]] or [[codeine]] can be used to relieve diarrhoea this way. A notable opioid for the purpose of relief of diarrhoea is [[loperamide]] which is only an agonist of the [[mu Opioid receptor|μ opioid receptor]]s in the large intestine and does not have opioid affects in the [[central nervous system]] as it doesn't cross the [[blood–brain barrier]] in significant amounts. This enables loperamide to be used to the same benefit as other opioid drugs but without the CNS side effects or potential for abuse. | * [[Opioid]]s' classical use besides pain relief is as an anti-diarrhoeal drug. Opioids have [[agonist]] actions on the intestinal opioid receptors, which when activated cause [[constipation]]. Drugs such as [[morphine]] or [[codeine]] can be used to relieve diarrhoea this way. A notable opioid for the purpose of relief of diarrhoea is [[loperamide]] which is only an agonist of the [[mu Opioid receptor|μ opioid receptor]]s in the large intestine and does not have opioid affects in the [[central nervous system]] as it doesn't cross the [[blood–brain barrier]] in significant amounts. This enables loperamide to be used to the same benefit as other opioid drugs but without the CNS side effects or potential for abuse. | ||
*[[Octreotide]] (somatostatin analogue) may be used in hospitalized patients to treat secretory diarrhea. | *[[Octreotide]] (somatostatin analogue) may be used in hospitalized patients to treat secretory diarrhea. | ||
* [[ | * Some [[probiotics]] are suggested as a possible treatment for various forms of [[gastroenteritis]]. As a treatment for infectious diarrhea, probiotics are of no benefit to people who have the condition for more than two days, and there is no evidence they lessen the duration of diarrhea overall. | ||
==See also== | ==See also== | ||
Latest revision as of 20:30, 17 April 2024
| 一般名 | 先発名 | 日本 | 創薬/開発 | 備考 |
|---|---|---|---|---|
| ラクトミン(エンテロコッカス・フェシウム) 酪酸菌(クロストリジウム・ブチリカム) 糖化菌(枯草菌) |
ビオスリー (PI) (IF) | 販売 | 鳥居薬品 | |
| ビフィズス菌(ビフィズス菌) | ラックビー (PI) (IF) | 販売 | 興和 |
Look up Antidiarrheal in Wiktionary, the free dictionary.
An anti-diarrheal drug (or anti-diarrhoeal drug in British English) is any medication which provides symptomatic relief for diarrhea.
Types
- Electrolyte solutions, while not true antidiarrheals, are used to replace lost fluids and salts in acute cases.
- Bulking agents like methylcellulose, guar gum or plant fibre (bran, sterculia, isabgol, etc.) are used for diarrhoea in functional bowel disease and to control ileostomy output.
- Absorbents absorb toxic substances that cause infective diarrhoea, methylcellulose is an absorbent.
- Anti-inflammatory compounds such as bismuth subsalicylate.
- Anticholinergics reduce intestinal movement and are effective against both diarrhoea and accompanying cramping.
- Opioids' classical use besides pain relief is as an anti-diarrhoeal drug. Opioids have agonist actions on the intestinal opioid receptors, which when activated cause constipation. Drugs such as morphine or codeine can be used to relieve diarrhoea this way. A notable opioid for the purpose of relief of diarrhoea is loperamide which is only an agonist of the μ opioid receptors in the large intestine and does not have opioid affects in the central nervous system as it doesn't cross the blood–brain barrier in significant amounts. This enables loperamide to be used to the same benefit as other opioid drugs but without the CNS side effects or potential for abuse.
- Octreotide (somatostatin analogue) may be used in hospitalized patients to treat secretory diarrhea.
- Some probiotics are suggested as a possible treatment for various forms of gastroenteritis. As a treatment for infectious diarrhea, probiotics are of no benefit to people who have the condition for more than two days, and there is no evidence they lessen the duration of diarrhea overall.
See also
- ATC code A07 Antidiarrheals, intestinal anti-inflammatory/anti-infective agents
Major chemical drug groups – based upon the Anatomical Therapeutic Chemical Classification System (Japanese version) | |
|---|---|
| gastrointestinal tract / metabolism (A) | |
| blood and blood forming organs (B) | |
| cardiovascular system (C) | |
| skin (D) | |
| genitourinary system (G) | |
| endocrine system (H) | |
| infections and infestations (J, P, QI) | |
| malignant disease (L01–L02) | |
| immune disease (L03–L04) | |
| muscles, bones, and joints (M) | |
| brain and nervous system (N) |
|
| respiratory system (R) | |
| sensory organs (S) | |
| other ATC (V) | |
 | この記事は、クリエイティブ・コモンズ・表示・継承ライセンス3.0のもとで公表されたウィキペディアの項目Antidiarrheal/en(14 January 2024編集記事参照)を素材として二次利用しています。 Lua error in Module:Itemnumber at line 91: attempt to concatenate local 'qid' (a nil value). |