Latest revision as of 17:18, 13 April 2024
Information about message (contribute ) This message has no documentation.
If you know where or how this message is used, you can help other translators by adding documentation to this message.
Message definition (Hyperlipidemia ) ! Defect
! Defect
! Increased lipoprotein
! Main symptoms
! Treatment
! Serum appearance
! Estimated prevalence
|-
!rowspan=3| Type I
! a
| 238600
| Buerger-Gruetz syndrome or familial hyperchylomicronemia
| Decreased lipoprotein lipase (LPL)
|rowspan=3| Chylomicrons
|rowspan=3| Acute pancreatitis , lipemia retinalis , eruptive skin xanthomas , hepatosplenomegaly
|rowspan=3| Diet control
|rowspan=3| Creamy top layer
|rowspan=3| One in 1,000,000
|-
! b
| 207750
| Familial apoprotein CII deficiency
| Altered ApoC2
|-
! c
| 118830
|
| LPL inhibitor in blood
|-
!rowspan=2| Type II
! a
| 143890
| Familial hypercholesterolemia
| LDL receptor deficiency
| LDL
| Xanthelasma , arcus senilis , tendon xanthomas
| Bile acid sequestrants , statins , niacin
| Clear
| One in 500 for heterozygotes
|-
! b
| 144250
| Familial combined hyperlipidemia
| Decreased LDL receptor and increased ApoB
| LDL and VLDL
|
| Statins, niacin, fibrate
| Turbid
| One in 100
|-
!colspan=2| Type III
| 107741
| Familial dysbetalipoproteinemia
| Defect in Apo E 2 synthesis
| IDL
| Tuberoeruptive xanthomas and palmar xanthomas
| Fibrate, statins
| Turbid
| One in 10,000
|-
!colspan=2| Type IV
| 144600
| Familial hypertriglyceridemia
| Increased VLDL production and decreased elimination
| VLDL
|Can cause pancreatitis at high triglyceride levels
| Fibrate, niacin, statins
| Turbid
| One in 100
|-
!colspan=2| Type V
| 144650
|
| Increased VLDL production and decreased LPL
| VLDL and chylomicrons
|
| Niacin, fibrate
| Creamy top layer and turbid bottom
|
|}