Translations:Nicotinamide riboside/4/en: Difference between revisions
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Latest revision as of 08:19, 8 April 2024
History
Nicotinamide riboside (NR) has been identified as an NAD precursor, involved in salvage NAD synthesis in both bacteria and eukaryotes. In bacteria, it was first described in 1944 as a necessary growth factor for the culture of Haemophilus influenza, H. influenza was identified as requiring both X factor (hemin) and V factor (NAD) to grow. V factor, purified from blood, was shown to exist in three forms: Nicotinamide adenine dinucleotide (NAD+), NMN and NR. NR was the compound that led to the most rapid growth of the H. influenza bacterium.