Translations:Amino acid/65/en: Difference between revisions

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Message definition (Amino acid)
Non-proteinogenic amino acids that are found in proteins are formed by [[post-translational modification]]. Such modifications can also determine the localization of the protein, e.g., the addition of long hydrophobic groups can cause a protein to bind to a [[phospholipid]] membrane. Examples:
*the [[carboxylation]] of [[glutamate]] allows for better binding of [[calcium in biology|calcium cations]], 
*[[Hydroxyproline]], generated by [[hydroxylation]] of [[proline]], is a major component of the [[connective tissue]] [[collagen]].
* [[Hypusine]] in the [[Eukaryotic initiation factor|translation initiation factor]] [[EIF5A]], contains a modification of lysine.

Non-proteinogenic amino acids that are found in proteins are formed by post-translational modification. Such modifications can also determine the localization of the protein, e.g., the addition of long hydrophobic groups can cause a protein to bind to a phospholipid membrane. Examples: