Translations:Cytochrome P450/19/en: Difference between revisions

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Message definition (Cytochrome P450)
====Drug interaction====
Many drugs may increase or decrease the activity of various P450 [[isozyme]]s either by inducing the biosynthesis of an isozyme ([[Regulation of gene expression|enzyme induction]]) or by directly inhibiting the activity of the P450 ([[enzyme inhibition]]). A classical example includes [[Anticonvulsant|anti-epileptic drugs]], such as [[phenytoin]], which induces [[CYP1A2]], [[CYP2C9]], [[CYP2C19]], and [[CYP3A4]].

Drug interaction

Many drugs may increase or decrease the activity of various P450 isozymes either by inducing the biosynthesis of an isozyme (enzyme induction) or by directly inhibiting the activity of the P450 (enzyme inhibition). A classical example includes anti-epileptic drugs, such as phenytoin, which induces CYP1A2, CYP2C9, CYP2C19, and CYP3A4.