Translations:Metformin/19/en: Difference between revisions

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Message definition (Metformin)
=== Gastric Cancer ===
Gastric cancer (GC) stands as a major global health concern due to its high prevalence and mortality rate. Amidst various treatment avenues, metformin, a common medication for type-2 [[diabetes mellitus]] (T2DM), has garnered attention for its potential anti-cancer properties. While its effectiveness in combating GC has been a subject of debate, recent clinical studies predominantly support metformin's protective impact on reducing the risk and improving the survival rates of GC patients. The drug's anti-cancer effects are believed to be mediated through multiple pathways, particularly involving AMPK activation and IGF-1R modulation. Despite promising findings, the consensus on metformin's application in GC prevention and treatment necessitates further clinical and mechanistic studies to confirm its therapeutic role.

Gastric Cancer

Gastric cancer (GC) stands as a major global health concern due to its high prevalence and mortality rate. Amidst various treatment avenues, metformin, a common medication for type-2 diabetes mellitus (T2DM), has garnered attention for its potential anti-cancer properties. While its effectiveness in combating GC has been a subject of debate, recent clinical studies predominantly support metformin's protective impact on reducing the risk and improving the survival rates of GC patients. The drug's anti-cancer effects are believed to be mediated through multiple pathways, particularly involving AMPK activation and IGF-1R modulation. Despite promising findings, the consensus on metformin's application in GC prevention and treatment necessitates further clinical and mechanistic studies to confirm its therapeutic role.