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Translations:Thiamine/1/en: Difference between revisions
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Message definition (
Thiamine
)
{{Pathnav|Dietary supplement|Vitamin|frame=1}}
{{Short description|Chemical compound}}
{{Infobox drug
| drug_name =
| INN =
| type = <!-- empty -->
| IUPAC_name = 2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
| image = Thiamin.svg
| width =
| alt =
| image2 = Thiamine-cation-from-xtal-3D-bs-17.png
| width2 =
| alt2 =
| imageL =
| widthL =
| altL =
| imageR =
| widthR =
| altR =
| caption = Skeletal formula and ball-and-stick model of the thiamine [[Ion#Anions and cations|cation]]
<!-- Clinical data -->| pronounce = {{IPAc-en|ˈ|θ|aɪ|.|ə|m|ᵻ|n}} {{respell|THY|ə-min}}
| tradename =
| Drugs.com = {{Drugs.com|monograph|thiamine-hydrochloride}}
| MedlinePlus =
| licence_EU = <!-- EMA requires brand name -->
| licence_US = Thiamine
| DailyMedID = Thiamine
| pregnancy_AU = <!-- A/B1/B2/B3/C/D/X -->
| pregnancy_AU_comment =
| pregnancy_category =
| dependency_liability =
| addiction_liability =
| routes_of_administration = by mouth, IV, IM
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
| legal_AU_comment =
| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_CA_comment =
| legal_DE = <!-- Anlage I, II, III or Unscheduled-->
| legal_DE_comment =
| legal_NZ = <!-- Class A, B, C -->
| legal_NZ_comment =
| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM / Class A, B, C -->
| legal_UK_comment =
| legal_US = OTC
| legal_US_comment =
| legal_UN = <!-- N I, II, III, IV / P I, II, III, IV-->
| legal_UN_comment =
| legal_status = <!--For countries not listed above-->
<!-- Pharmacokinetic data -->| bioavailability = 3.7% to 5.3% (Thiamine hydrochloride)
| protein_bound =
| metabolism =
| metabolites =
| onset =
| elimination_half-life =
| duration_of_action =
| excretion = <!-- Identifiers -->
| CAS_number_Ref = {{cascite|correct|CAS}}
| CAS_number = 70-16-6
| index_label = cation
| index2_label = Cl<sup>−</sup> salt
| CAS_number2_Ref = {{cascite|correct|CAS}}
| CAS_number2 = 59-43-8
| CAS_supplemental =<br>{{CAS|67-03-8}}(Cl<sup>−</sup>.HCl)
| UNII2_Ref = {{fdacite|correct|FDA}}
| UNII2 = X66NSO3N35
| class = [[vitamin]]
| ATCvet =
| ATC_prefix = A11
| ATC_suffix = DA01
| ATC_supplemental =
| PubChem = 1130
| PubChem2 = 6042
| IUPHAR_ligand =
| DrugBank = DB00152
| ChemSpiderID = 1098
| UNII = 4ABT0J945J
| KEGG = C00378
| ChEBI = 18385
| ChEMBL = 1547
| NIAID_ChemDB =
| synonyms = Vitamin B<sub>1</sub>, aneurine, thiamin
<!-- Chemical and physical data -->| chemical_formula = | C= 12| H= 17| N= 4| O= 1| S= 1
| charge = +
| SMILES = Cc2ncc(C[n+]1csc(CCO)c1C)c(N)n2
| Jmol =
| StdInChI = 1S/C12H17N4OS/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15)/q+1
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = JZRWCGZRTZMZEH-UHFFFAOYSA-N
<!--| InChIKey1 = MYVIATVLJGTBFV-UHFFFAOYSA-M
| InChIKey2 = DPJRMOMPQZCRJU-UHFFFAOYSA-M
StdInChI and key are for cation, extra Inchikey for Cl- salt and Cl-.HCl, so search engines will find this page. Source=CAS -->
| density =
| density_notes =
| melting_point =
| melting_high =
| melting_notes =
| boiling_point =
| boiling_notes =
| solubility =
| specific_rotation =
}}
Dietary supplement > Vitamin >
Thiamine/1/en
Chemical compound
Thiamine/1/en
Skeletal formula and ball-and-stick model of the thiamine
cation
Clinical data
Pronunciation
/
ˈ
θ
aɪ
.
ə
m
ɪ
n
/
THY
-ə-min
Other names
Vitamin B
1
, aneurine, thiamin
AHFS
/
Drugs.com
Monograph
License data
US
DailyMed
:
Thiamine
US
FDA
:
Thiamine
Routes of
administration
by mouth, IV, IM
Drug class
vitamin
ATC code
cation:
A11DA01
(
WHO
)
Legal status
Legal status
US
:
OTC
Pharmacokinetic
data
Bioavailability
3.7% to 5.3% (Thiamine hydrochloride)
Identifiers
IUPAC name
2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
CAS Number
cation:
70-16-6
Y
67-03-8
(Cl
−
.HCl)
Cl
−
salt:
59-43-8
Y
PubChem
CID
cation:
1130
Cl
−
salt:
6042
DrugBank
cation:
DB00152
ChemSpider
cation:
1098
UNII
cation:
4ABT0J945J
Cl
−
salt:
X66NSO3N35
Y
KEGG
cation:
C00378
ChEBI
cation:
CHEBI:18385
ChEMBL
cation:
ChEMBL1547
Chemical and physical data
Formula
C
12
H
17
N
4
O
S
+
Molar mass
265.36
g·mol
−1
3D model (
JSmol
)
cation:
Interactive image
SMILES
cation: Cc2ncc(C[n+]1csc(CCO)c1C)c(N)n2
InChI
cation: InChI=1S/C12H17N4OS/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15)/q+1
Y
Key:JZRWCGZRTZMZEH-UHFFFAOYSA-N
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