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Message definition (Vitamin D ) ==Mechanism of action== === Metabolic activation === [[File:Cholecalciferol_to_calcidiol_CH3.svg|thumb|upright=1.35|Liver hydroxylation of [[cholecalciferol]] to [[calcifediol]] ]] [[File:Calcidiol_to_calcitriol_CH3.svg|thumb|upright=1.35|Kidney hydroxylation of calcifediol to [[calcitriol]] ]] Vitamin D is carried via the blood to the liver, where it is converted into the [[prohormone]] [[calcifediol]]. Circulating calcifediol may then be converted into [[calcitriol]] {{ndash}} the biologically active form of vitamin D {{ndash}} in the kidneys.
Mechanism of action
Metabolic activation
Liver hydroxylation of cholecalciferol to calcifediol
Kidney hydroxylation of calcifediol to calcitriol
Vitamin D is carried via the blood to the liver, where it is converted into the prohormone calcifediol . Circulating calcifediol may then be converted into calcitriol – the biologically active form of vitamin D – in the kidneys.