Vitamin D - Revision history

Fire at 11:03, 4 February 2024

2024-02-04T11:03:23Z

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Fire at 23:40, 25 January 2024

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Fire at 07:25, 24 January 2024

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	Several forms ([[vitamer]]s) of vitamin D exist. The two major forms are vitamin D<sub>2</sub> or ergocalciferol, and vitamin D<sub>3</sub> or cholecalciferol. Vitamin D without a subscript refers to either D<sub>2</sub> or D<sub>3</sub>, or both, and is known collectively as calciferol.~~{{citation needed\|date=April 2023}}~~		Several forms ([[vitamer]]s) of vitamin D exist. The two major forms are vitamin D<sub>2</sub> or ergocalciferol, and vitamin D<sub>3</sub> or cholecalciferol. Vitamin D without a subscript refers to either D<sub>2</sub> or D<sub>3</sub>, or both, and is known collectively as calciferol.

	Vitamin D<sub>2</sub> was chemically characterized in 1931. In 1935, the [[chemical structure]] of vitamin D<sub>3</sub> was defined and shown to result from the [[ultraviolet\|ultraviolet irradiation]] of 7-dehydrocholesterol. A chemical nomenclature for vitamin D forms was recommended in 1981, but alternative names remain in common use.		Vitamin D<sub>2</sub> was chemically characterized in 1931. In 1935, the [[chemical structure]] of vitamin D<sub>3</sub> was defined and shown to result from the [[ultraviolet\|ultraviolet irradiation]] of 7-dehydrocholesterol. A chemical nomenclature for vitamin D forms was recommended in 1981, but alternative names remain in common use.

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	A meta-analysis of three studies on the effect of oral vitamin D or calcifediol supplementation indicated a lower [[intensive care unit]] (ICU) admission rate ([[odds ratio]]: 0.36) compared to those without supplementation, but without a change in mortality. A Cochrane review, also of three studies, found the evidence for the effectiveness of vitamin D supplementation for the treatment of COVID-19 to be very uncertain. They found there was substantial clinical and methodological heterogeneity in the three studies that were included, mainly because of different supplementation strategies, vitamin D formulations (one using calcifediol), pre-treatment status and reported outcomes. Another meta-analysis stated that the use of high doses of vitamin D in people with COVID-19 is not based on solid evidence although calcifediol supplementation may have a protective effect on ICU admissions.		A meta-analysis of three studies on the effect of oral vitamin D or calcifediol supplementation indicated a lower [[intensive care unit]] (ICU) admission rate ([[odds ratio]]: 0.36) compared to those without supplementation, but without a change in mortality. A Cochrane review, also of three studies, found the evidence for the effectiveness of vitamin D supplementation for the treatment of COVID-19 to be very uncertain. They found there was substantial clinical and methodological heterogeneity in the three studies that were included, mainly because of different supplementation strategies, vitamin D formulations (one using calcifediol), pre-treatment status and reported outcomes. Another meta-analysis stated that the use of high doses of vitamin D in people with COVID-19 is not based on solid evidence although calcifediol supplementation may have a protective effect on ICU admissions.

	~~== External links ==~~
	~~{{Scholia}}~~

	{{Vitamins}}		{{Vitamins}}

Fire: Created page with "{{Short description|Group of fat-soluble secosteroids}} {{Infobox drug class |Synonyms= Calciferols | Image = Cholecalciferol2.svg | Alt = | Caption = Cholecalciferol (D₃) | Use = Rickets, osteoporosis, vitamin D deficiency | MeshID = D014807 | Consumer_Reports = | ATC_prefix = A11CC | medicinenet = | rxlist = | Drugs.com = {{Drugs.com|npp|vitamin-d}} | Biological_target = vitamin D receptor }} '''Vitam..."

2024-01-24T07:24:19Z

Created page with "{{Short description|Group of fat-soluble secosteroids}} {{Infobox drug class |Synonyms= Calciferols | Image = Cholecalciferol2.svg | Alt = | Caption = Cholecalciferol (D<sub>3</sub>) | Use = Rickets, osteoporosis, vitamin D deficiency | MeshID = D014807 | Consumer_Reports = | ATC_prefix = A11CC | medicinenet = | rxlist = | Drugs.com = {{Drugs.com|npp|vitamin-d}} | Biological_target = vitamin D receptor }} '''Vitam..."

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