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	<title>Translations:Weight management/33/en - Revision history</title>
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		<title>FuzzyBot: Importing a new version from external source</title>
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&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;==== Commonly associated with weight gain ====&lt;br /&gt;
Polycystic ovary syndrome (PCOS), which is characterized by [[insulin resistance]] and [[hyperandrogenism]], is a common condition that has been linked to obesity. A combination of genetics, lifestyle, and environment appear to contribute to the hormonal changes responsible for weight gain and obesity seen in individuals with PCOS. There appears to be a bidirectional relationship between obesity and PCOS, whereby PCOS increases the risk of obesity and similarly, obesity has been found to exacerbate PCOS hormonal differences and clinical symptoms.&lt;br /&gt;
Obesity has been linked with pancreatic [[Beta cell|β-cell]] dysfunction and insulin resistance. In diabetes, impaired β-islet cells are responsible for the lack of blood glucose control. Individuals with a higher body mass index concerning for obesity may have increased levels of hormones, proinflammatory markers, and glycerol, which can contribute to insulin resistance. The combined effects of impaired pancreatic β-islet cells and insulin resistance increase the likelihood of developing diabetes.&lt;/div&gt;</summary>
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