https://wiki.tiffa.net/w/index.php?action=history&feed=atom&title=Translations%3AVitamin_D5%2F1%2Fja 2026-05-11T21:09:01Z Revision history for this page on the wiki MediaWiki 1.43.0 https://wiki.tiffa.net/w/index.php?title=Translations:Vitamin_D5/1/ja&diff=136997&oldid=prev 2024-04-10T12:39:25Z

<p>Created page with &quot;{{DISPLAYTITLE:ビタミンD&lt;sub&gt;5&lt;/sub&gt;}} {{chembox | Verifiedfields = changed | verifiedrevid = 470631138 | Name=Vitamin D&lt;sub&gt;5&lt;/sub&gt; | ImageFile=Vitamin D5 structure.svg | ImageSize= | IUPACName=(1&#039;&#039;S&#039;&#039;,3&#039;&#039;Z&#039;&#039;)-3-[(2&#039;&#039;E&#039;&#039;)-2-[(1&#039;&#039;R&#039;&#039;,3a&#039;&#039;S&#039;&#039;,7a&#039;&#039;R&#039;&#039;)-1-[(1&#039;&#039;R&#039;&#039;,4&#039;&#039;S&#039;&#039;)-4-ethyl-1,5-dimethylhexyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1&#039;&#039;H&#039;&#039;-inden-4-ylidene]ethylidene]-4-methylene-1-cyclohexanol | OtherNames= Sitocalciferol &lt;br&gt; (5&#039;&#039;Z&#039;&#039;,7&#039;&#039;E&#039;&#039;)-(3&#039;&#039;S&#039;&#039;)-9,10-secoporiferasta...&quot;</p> <p><b>New page</b></p><div>{{DISPLAYTITLE:ビタミンD&lt;sub&gt;5&lt;/sub&gt;}}<br /> {{chembox<br /> | Verifiedfields = changed<br /> | verifiedrevid = 470631138<br /> | Name=Vitamin D&lt;sub&gt;5&lt;/sub&gt;<br /> | ImageFile=Vitamin D5 structure.svg<br /> | ImageSize=<br /> | IUPACName=(1&#039;&#039;S&#039;&#039;,3&#039;&#039;Z&#039;&#039;)-3-[(2&#039;&#039;E&#039;&#039;)-2-[(1&#039;&#039;R&#039;&#039;,3a&#039;&#039;S&#039;&#039;,7a&#039;&#039;R&#039;&#039;)-1-[(1&#039;&#039;R&#039;&#039;,4&#039;&#039;S&#039;&#039;)-4-ethyl-1,5-dimethylhexyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1&#039;&#039;H&#039;&#039;-inden-4-ylidene]ethylidene]-4-methylene-1-cyclohexanol<br /> | OtherNames= Sitocalciferol &lt;br&gt; (5&#039;&#039;Z&#039;&#039;,7&#039;&#039;E&#039;&#039;)-(3&#039;&#039;S&#039;&#039;)-9,10-secoporiferasta-5,7,10(19)-trien-3-ol<br /> |Section1={{Chembox Identifiers<br /> | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}<br /> | ChemSpiderID = 7826639<br /> | ChEBI = 33279<br /> | InChI = 1/C29H48O/c1-7-23(20(2)3)12-10-22(5)27-16-17-28-24(9-8-18-29(27,28)6)13-14-25-19-26(30)15-11-21(25)4/h13-14,20,22-23,26-28,30H,4,7-12,15-19H2,1-3,5-6H3/b24-13+,25-14-/t22-,23+,26+,27-,28+,29-/m1/s1<br /> | InChIKey = RMDJVOZETBHEAR-GHTRHTQZBN<br /> | StdInChI_Ref = {{stdinchicite|correct|chemspider}}<br /> | StdInChI = 1S/C29H48O/c1-7-23(20(2)3)12-10-22(5)27-16-17-28-24(9-8-18-29(27,28)6)13-14-25-19-26(30)15-11-21(25)4/h13-14,20,22-23,26-28,30H,4,7-12,15-19H2,1-3,5-6H3/b24-13+,25-14-/t22-,23+,26+,27-,28+,29-/m1/s1<br /> | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}<br /> | StdInChIKey = RMDJVOZETBHEAR-GHTRHTQZSA-N<br /> | CASNo_Ref = {{cascite|correct|CAS}}<br /> | CASNo=71761-06-3<br /> | UNII_Ref = {{fdacite|correct|FDA}}<br /> | UNII = 0W2I161LCL<br /> | PubChem=9547700<br /> | SMILES = O[C@@H]1CC(\C(=C)CC1)=C\C=C2/CCC[C@]3([C@H]2CC[C@@H]3[C@H](C)CC[C@H](CC)C(C)C)C<br /> }}<br /> |Section2={{Chembox Properties<br /> | C=29 | H=48 | O=1<br /> | Appearance=<br /> | Density=<br /> | MeltingPt=<br /> | BoilingPt=<br /> | Solubility=<br /> }}<br /> |Section3={{Chembox Hazards<br /> | MainHazards=<br /> | FlashPt=<br /> | AutoignitionPt =<br /> }}<br /> }}<br /> &#039;&#039;&#039;ビタミンD&lt;sub&gt;5&lt;/sub&gt;&#039;&#039;&#039;（&#039;&#039;&#039;sitocalciferol&#039;&#039;&#039;）は[[vitamin D/ja|ビタミンD]]の一種である。<br /> <br /> == 研究{{Anchor|Research}} ==<br /> ビタミンD&lt;sub&gt;3&lt;/sub&gt;の一種である[[calcitriol/ja|カルシトリオール]]の[[structural analog/ja|アナログ]]が抗腫瘍剤として使用されることが提案されている。ビタミンD&lt;sub&gt;3&lt;/sub&gt;に関する研究では、[[prostate cancer/ja|前立腺がん]]における細胞増殖の阻害が示されているが、ビタミンD&lt;sub&gt;3&lt;/sub&gt;の高用量投与は[[Hypercalcaemia/ja|高カルシウム血症]]を引き起こす。前立腺がんに対するビタミンD&lt;sub&gt;5&lt;/sub&gt;の効果も研究されており、ビタミンD&lt;sub&gt;3&lt;/sub&gt;とは異なり、ビタミンD&lt;sub&gt;5&lt;/sub&gt;は腫瘍細胞の増殖を阻害する一方で[[Hypercalcaemia/ja|高カルシウム血症]]を引き起こさない。抗腫瘍剤として最も研究されているビタミンD&lt;sub&gt;5&lt;/sub&gt;の類似体は1α-ヒドロキシビタミンD&lt;sub&gt;5.&lt;/sub&gt;である。</div>

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