https://wiki.tiffa.net/w/index.php?action=history&feed=atom&title=Translations%3AVitamin_D%2F11%2FenTranslations:Vitamin D/11/en - Revision history2026-08-14T00:53:10ZRevision history for this page on the wikiMediaWiki 1.43.0https://wiki.tiffa.net/w/index.php?title=Translations:Vitamin_D/11/en&diff=110136&oldid=prevFuzzyBot: Importing a new version from external source2024-01-25T23:41:39Z<p>Importing a new version from external source</p>
<p><b>New page</b></p><div>== Biology ==<br />
[[File:Calcium regulation.png|thumb|[[Calcium metabolism|Calcium regulation]] in the human body. The role of active vitamin D (1,25-dihydroxyvitamin D, calcitriol) is shown in orange.]]<br />
The active vitamin D metabolite calcitriol mediates its biological effects by binding to the [[vitamin D receptor]] (VDR), which is principally located in the [[Cell nucleus|nuclei]] of target cells. The binding of calcitriol to the VDR allows the VDR to act as a [[transcription factor]] that modulates the [[gene expression]] of transport proteins (such as [[TRPV6]] and [[calbindin]]), which are involved in calcium absorption in the intestine. The vitamin D receptor belongs to the [[nuclear receptor]] superfamily of [[steroid hormone receptor|steroid/thyroid hormone receptors]], and VDRs are expressed by cells in most [[organ (biology)|organs]], including the brain, heart, skin, gonads, prostate and breast.</div>FuzzyBot