https://wiki.tiffa.net/w/index.php?action=history&feed=atom&title=Translations%3AVitamin_B6%2F47%2Fen 2026-07-08T19:07:56Z Revision history for this page on the wiki MediaWiki 1.43.0 https://wiki.tiffa.net/w/index.php?title=Translations:Vitamin_B6/47/en&diff=133942&oldid=prev 2024-04-03T07:32:26Z

<p>Importing a new version from external source</p> <p><b>New page</b></p><div>==History==<br /> {{Further|Vitamin#History}}<br /> An overview of the history was published in 2012. In 1934, the Hungarian physician [[Paul Gyorgy|Paul György]] discovered a substance that was able to cure a skin disease in rats (dermatitis acrodynia). He named this substance vitamin B&lt;sub&gt;6&lt;/sub&gt;, as numbering of the B vitamins was chronological, and [[pantothenic acid]] had been assigned vitamin B&lt;sub&gt;5&lt;/sub&gt; in 1931. In 1938, [[Richard Kuhn]] was awarded the [[Nobel Prize in Chemistry]] for his work on carotenoids and vitamins, specifically B&lt;sub&gt;2&lt;/sub&gt; and B&lt;sub&gt;6&lt;/sub&gt;. Also in 1938, Samuel Lepkovsky isolated vitamin B&lt;sub&gt;6&lt;/sub&gt; from rice bran. A year later, Stanton A. Harris and [[Karl August Folkers]] determined the structure of pyridoxine and reported success in [[chemical synthesis]], and then in 1942 [[Esmond Emerson Snell]] developed a microbiological growth [[assay]] that led to the characterization of pyridoxamine, the aminated product of pyridoxine, and pyridoxal, the [[formyl]] derivative of pyridoxine. Further studies showed that pyridoxal, pyridoxamine, and pyridoxine have largely equal activity in animals and owe their vitamin activity to the ability of the organism to convert them into the enzymatically active form pyridoxal-5-phosphate.</div>

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