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	<title>Translations:Vitamin B6/43/en - Revision history</title>
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	<updated>2026-05-15T20:39:51Z</updated>
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		<title>FuzzyBot: Importing a new version from external source</title>
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		<summary type="html">&lt;p&gt;Importing a new version from external source&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;===Diagnosis===&lt;br /&gt;
The assessment of vitamin B&amp;lt;sub&amp;gt;6&amp;lt;/sub&amp;gt; status is essential, as the clinical signs and symptoms in less severe cases are not specific. The three biochemical tests most widely used are plasma PLP concentrations, the activation coefficient for the erythrocyte enzyme aspartate aminotransferase, and the urinary excretion of vitamin B&amp;lt;sub&amp;gt;6&amp;lt;/sub&amp;gt; degradation products, specifically urinary PA. Of these, plasma PLP is probably the best single measure, because it reflects tissue stores. Plasma PLP of less than 10&amp;amp;nbsp;nmol/L is indicative of vitamin B&amp;lt;sub&amp;gt;6&amp;lt;/sub&amp;gt; deficiency. A PLP concentration greater than 20&amp;amp;nbsp;nmol/L has been chosen as a level of adequacy for establishing Estimated Average Requirements and Recommended Daily Allowances in the USA. Urinary PA is also an indicator of vitamin B&amp;lt;sub&amp;gt;6&amp;lt;/sub&amp;gt; deficiency; levels of less than 3.0&amp;amp;nbsp;mmol/day is suggestive of vitamin B&amp;lt;sub&amp;gt;6&amp;lt;/sub&amp;gt; deficiency. Other methods of measurement, including [[Ultraviolet–visible spectroscopy|UV spectrometric]], [[Fluorescence spectroscopy|spectrofluorimetric]], [[Mass spectrometry|mass spectrometric]], [[thin-layer chromatography|thin-layer]] and [[High-performance liquid chromatography|high-performance liquid chromatographic]], [[Electrophoresis|electrophoretic]], [[electrochemistry|electrochemical]], and enzymatic, have been developed.&lt;/div&gt;</summary>
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