https://wiki.tiffa.net/w/index.php?action=history&feed=atom&title=Translations%3AVitamin_B12%2F71%2Fen 2026-05-11T20:14:51Z Revision history for this page on the wiki MediaWiki 1.43.0 https://wiki.tiffa.net/w/index.php?title=Translations:Vitamin_B12/71/en&diff=135265&oldid=prev 2024-04-05T11:15:36Z

<p>Importing a new version from external source</p> <p><b>New page</b></p><div>===Storage and excretion===<br /> How fast B&lt;sub&gt;12&lt;/sub&gt; levels change depends on the balance between how much B&lt;sub&gt;12&lt;/sub&gt; is obtained from the diet, how much is secreted and how much is absorbed. The total amount of vitamin B&lt;sub&gt;12&lt;/sub&gt; stored in the body is about 2–5{{nbsp}}mg in adults. Around 50% of this is stored in the liver. Approximately 0.1% of this is lost per day by secretions into the gut, as not all these secretions are reabsorbed. [[Bile]] is the main form of B&lt;sub&gt;12&lt;/sub&gt; excretion; most of the B&lt;sub&gt;12&lt;/sub&gt; secreted in the bile is recycled via [[enterohepatic circulation]]. Excess B&lt;sub&gt;12&lt;/sub&gt; beyond the blood&#039;s binding capacity is typically excreted in urine. Owing to the extremely efficient enterohepatic circulation of B&lt;sub&gt;12&lt;/sub&gt;, the liver can store 3 to 5 years&#039; worth of vitamin B&lt;sub&gt;12&lt;/sub&gt;; therefore, nutritional deficiency of this vitamin is rare in adults in the absence of malabsorption disorders. In the absence of enterohepatic reabsorption, only months to a year of vitamin B&lt;sub&gt;12&lt;/sub&gt; are stored.</div>

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