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	<id>https://wiki.tiffa.net/w/index.php?action=history&amp;feed=atom&amp;title=Translations%3ASGLT2_inhibitor%2F23%2Fja</id>
	<title>Translations:SGLT2 inhibitor/23/ja - Revision history</title>
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	<updated>2026-10-12T04:35:42Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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	<entry>
		<id>https://wiki.tiffa.net/w/index.php?title=Translations:SGLT2_inhibitor/23/ja&amp;diff=114116&amp;oldid=prev</id>
		<title>Fire at 12:14, 12 February 2024</title>
		<link rel="alternate" type="text/html" href="https://wiki.tiffa.net/w/index.php?title=Translations:SGLT2_inhibitor/23/ja&amp;diff=114116&amp;oldid=prev"/>
		<updated>2024-02-12T12:14:09Z</updated>

		<summary type="html">&lt;p&gt;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
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				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
				&lt;tr class=&quot;diff-title&quot; lang=&quot;en&quot;&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 21:14, 12 February 2024&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l2&quot;&gt;Line 2:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 2:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|+ 表2: 様々なSGLT-2阻害剤の薬物動態パラメータ&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|+ 表2: 様々なSGLT-2阻害剤の薬物動態パラメータ&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|-&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|-&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;! 薬物名 !! 生物学的利用能 !! タンパク質結合 !! &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;最大（時間） &lt;/del&gt;!! t1/2 (hours) !! Cmax !! SGLT1に対するSGLT2選択性&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;! 薬物名 !! 生物学的利用能 !! タンパク質結合 !! &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;tmax（時間） &lt;/ins&gt;!! t1/2 (hours) !! Cmax !! SGLT1に対するSGLT2選択性&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|-&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|-&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;| [[Canagliflozin/ja]] || 65% (300&amp;amp;nbsp;mg dose) || 99% || 1–2 || 10.6 (100&amp;amp;nbsp;mg dose); 13.1 (300&amp;amp;nbsp;mg dose) || 1096&amp;amp;nbsp;ng/mL (100&amp;amp;nbsp;mg dose); 3480&amp;amp;nbsp;ng/mL (300&amp;amp;nbsp;mg dose) || 250 fold&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;| [[Canagliflozin/ja]] || 65% (300&amp;amp;nbsp;mg dose) || 99% || 1–2 || 10.6 (100&amp;amp;nbsp;mg dose); 13.1 (300&amp;amp;nbsp;mg dose) || 1096&amp;amp;nbsp;ng/mL (100&amp;amp;nbsp;mg dose); 3480&amp;amp;nbsp;ng/mL (300&amp;amp;nbsp;mg dose) || 250 fold&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>Fire</name></author>
	</entry>
	<entry>
		<id>https://wiki.tiffa.net/w/index.php?title=Translations:SGLT2_inhibitor/23/ja&amp;diff=114107&amp;oldid=prev</id>
		<title>Fire: Created page with &quot;{| class=&quot;wikitable&quot; |+ 表2: 様々なSGLT-2阻害剤の薬物動態パラメータ |- ! 薬物名 !! 生物学的利用能 !! タンパク質結合 !! 最大（時間） !! t1/2 (hours) !! Cmax !! SGLT1に対するSGLT2選択性 |- | Canagliflozin/ja || 65% (300&amp;nbsp;mg dose) || 99% || 1–2 || 10.6 (100&amp;nbsp;mg dose); 13.1 (300&amp;nbsp;mg dose) || 1096&amp;nbsp;ng/mL (100&amp;nbsp;mg dose); 3480&amp;nbsp;ng/mL (300&amp;nbsp;mg dose) || 250 fold |- | Dapagliflozin/ja || 78% || 91...&quot;</title>
		<link rel="alternate" type="text/html" href="https://wiki.tiffa.net/w/index.php?title=Translations:SGLT2_inhibitor/23/ja&amp;diff=114107&amp;oldid=prev"/>
		<updated>2024-02-12T12:12:01Z</updated>

		<summary type="html">&lt;p&gt;Created page with &amp;quot;{| class=&amp;quot;wikitable&amp;quot; |+ 表2: 様々なSGLT-2阻害剤の薬物動態パラメータ |- ! 薬物名 !! 生物学的利用能 !! タンパク質結合 !! 最大（時間） !! t1/2 (hours) !! Cmax !! SGLT1に対するSGLT2選択性 |- | &lt;a href=&quot;/w/index.php?title=Canagliflozin/ja&amp;amp;action=edit&amp;amp;redlink=1&quot; class=&quot;new&quot; title=&quot;Canagliflozin/ja (page does not exist)&quot;&gt;Canagliflozin/ja&lt;/a&gt; || 65% (300 mg dose) || 99% || 1–2 || 10.6 (100 mg dose); 13.1 (300 mg dose) || 1096 ng/mL (100 mg dose); 3480 ng/mL (300 mg dose) || 250 fold |- | &lt;a href=&quot;/w/index.php?title=Dapagliflozin/ja&amp;amp;action=edit&amp;amp;redlink=1&quot; class=&quot;new&quot; title=&quot;Dapagliflozin/ja (page does not exist)&quot;&gt;Dapagliflozin/ja&lt;/a&gt; || 78% || 91...&amp;quot;&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;{| class=&amp;quot;wikitable&amp;quot;&lt;br /&gt;
|+ 表2: 様々なSGLT-2阻害剤の薬物動態パラメータ&lt;br /&gt;
|-&lt;br /&gt;
! 薬物名 !! 生物学的利用能 !! タンパク質結合 !! 最大（時間） !! t1/2 (hours) !! Cmax !! SGLT1に対するSGLT2選択性&lt;br /&gt;
|-&lt;br /&gt;
| [[Canagliflozin/ja]] || 65% (300&amp;amp;nbsp;mg dose) || 99% || 1–2 || 10.6 (100&amp;amp;nbsp;mg dose); 13.1 (300&amp;amp;nbsp;mg dose) || 1096&amp;amp;nbsp;ng/mL (100&amp;amp;nbsp;mg dose); 3480&amp;amp;nbsp;ng/mL (300&amp;amp;nbsp;mg dose) || 250 fold&lt;br /&gt;
|-&lt;br /&gt;
| [[Dapagliflozin/ja]] || 78% || 91% || 1–1.5 || 12.9 || 79.6&amp;amp;nbsp;ng/mL (5&amp;amp;nbsp;mg dose); 165.0&amp;amp;nbsp;ng/mL (10&amp;amp;nbsp;mg dose) || 1200 fold&lt;br /&gt;
|-&lt;br /&gt;
| [[Empagliflozin/ja]] || 90–97% (mice); 89% (dogs); 31% (rats) || 86.20% || 1.5 || 13.2 (10&amp;amp;nbsp;mg dose); 13.3h (25&amp;amp;nbsp;mg dose) || 259nmol/L (10&amp;amp;nbsp;mg dose); 687nmol/L (25&amp;amp;nbsp;mg dose) || 2500 fold&lt;br /&gt;
|-&lt;br /&gt;
| [[Ertugliflozin/ja]] || 70-90% || 95% || 0.5-1.5 || 11-17 ||268&amp;amp;nbsp;ng/mL (15&amp;amp;nbsp;mg dose) || 2000 fold&lt;br /&gt;
|-&lt;br /&gt;
| [[Ipragliflozin/ja]] (50&amp;amp;nbsp;mg) || 90% || 96.30% || 1 || 15–16 (50&amp;amp;nbsp;mg dose) || 975&amp;amp;nbsp;ng/mL || 360 fold&lt;br /&gt;
|-&lt;br /&gt;
| [[Luseogliflozin/ja]] || 35.3% (male rats); 58.2% (female rats); 92.7% (male dogs) || 96.0–96.3% || 0.625±0.354 || 9.24±0.928 || 119±27.0&amp;amp;nbsp;ng/mL || 1650 fold&lt;br /&gt;
|-&lt;/div&gt;</summary>
		<author><name>Fire</name></author>
	</entry>
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