https://wiki.tiffa.net/w/index.php?action=history&feed=atom&title=Translations%3ARenin%E2%80%93angiotensin_system%2F12%2FenTranslations:Renin–angiotensin system/12/en - Revision history2026-07-14T18:51:25ZRevision history for this page on the wikiMediaWiki 1.43.0https://wiki.tiffa.net/w/index.php?title=Translations:Renin%E2%80%93angiotensin_system/12/en&diff=131399&oldid=prevFuzzyBot: Importing a new version from external source2024-03-27T00:15:47Z<p>Importing a new version from external source</p>
<p><b>New page</b></p><div>==Local renin–angiotensin systems==<br />
Locally expressed renin–angiotensin systems have been found in a number of tissues, including the [[kidney]]s, [[adrenal gland]]s, the [[heart]], [[vasculature]] and [[nervous system]], and have a variety of functions, including [[Local blood flow regulation|local cardiovascular regulation]], in association or independently of the systemic renin–angiotensin system, as well as non-cardiovascular functions. Outside the kidneys, renin is predominantly picked up from the circulation but may be secreted locally in some tissues; its precursor prorenin is highly expressed in tissues and more than half of circulating prorenin is of extrarenal origin, but its physiological role besides serving as precursor to renin is still unclear. Outside the liver, angiotensinogen is picked up from the circulation or expressed locally in some tissues; with renin they form angiotensin I, and locally expressed [[angiotensin-converting enzyme]], [[chymase]] or other enzymes can transform it into angiotensin II. This process can be intracellular or interstitial.</div>FuzzyBot