https://wiki.tiffa.net/w/index.php?action=history&feed=atom&title=Translations%3APyridoxal_phosphate%2F29%2FenTranslations:Pyridoxal phosphate/29/en - Revision history2026-11-09T22:12:32ZRevision history for this page on the wikiMediaWiki 1.43.0https://wiki.tiffa.net/w/index.php?title=Translations:Pyridoxal_phosphate/29/en&diff=134332&oldid=prevFuzzyBot: Importing a new version from external source2024-04-03T12:34:51Z<p>Importing a new version from external source</p>
<p><b>New page</b></p><div>==Evolution==<br />
[[Pyridoxal 5-phosphate|Pyridoxal-5-phosphate (vitamin B6)]]-dependent enzymes have multiple evolutionary origins. The overall [[Vitamin B6|B6 enzymes]] diverged into four independent evolutionary lines: α family (i.e. [[Aspartate transaminase|aspartate aminotransferase]]), β family ([[serine dehydratase]]),D-[[alanine aminotransferase]] family and the [[alanine racemase]] family. An example of the evolutionary similarity in the Beta family is seen in the mechanism. The β enzymes are all [[lyase]]s and catalyze reactions where Cα and Cβ participate. Overall, in the [[Vitamin B6|PLP]]-dependent enzymes, the PLP in every case is covalently attached via an imine bond to the amino group in the active site.</div>FuzzyBot