https://wiki.tiffa.net/w/index.php?action=history&feed=atom&title=Translations%3APyridoxal_phosphate%2F28%2FenTranslations:Pyridoxal phosphate/28/en - Revision history2026-08-25T08:15:25ZRevision history for this page on the wikiMediaWiki 1.43.0https://wiki.tiffa.net/w/index.php?title=Translations:Pyridoxal_phosphate/28/en&diff=134331&oldid=prevFuzzyBot: Importing a new version from external source2024-04-03T12:34:51Z<p>Importing a new version from external source</p>
<p><b>New page</b></p><div>Examples of inhibitors:<br />
* [[Levothyroxine]] In rats given only 10&nbsp;µg of D, L-thyroxine daily for 15 days, liver cysteine desulfhydrase activity disappears and serine and threonine dehydrase and alanine glutamate transaminase activities decrease about 40%. Either in vivo feeding of pyridoxal-5-phosphate or in vitro addition of the coenzyme to the liver preparations restores full activity to all these enzymes, and the slight in vitro inhibition in the presence of 10<sup>−5</sup> M thyroxine is also reversed by pyridoxal-5-phosphate.<br />
* The inactive form [[pyridoxine]] competitively inhibits the active pyridoxal-5'-phosphate. Consequently, symptoms of vitamin B6 supplementation in the pyridoxine form can mimic those of vitamin B6 deficiency; an effect which perhaps might be avoided by supplementing with P5P instead.<br />
* AlaP (alanine phosphonate) inhibits [[alanine racemase]]s, but its lack of specificity has prompted further designs of ALR inhibitors.<br />
* [[Gabaculine]] and [[Vigabatrin]] inhibit [[GABA aminotransferase]]<br />
* [[Canaline]] and 5-fluoromethylornithine inhibit [[ornithine aminotransferase]]<br />
* Amino-oxy SAM inhibits [[1-aminocyclopropane-1-carboxylate synthase|ACC synthase]]</div>FuzzyBot