https://wiki.tiffa.net/w/index.php?action=history&feed=atom&title=Translations%3APantothenic_acid%2F20%2FenTranslations:Pantothenic acid/20/en - Revision history2026-09-08T16:32:34ZRevision history for this page on the wikiMediaWiki 1.43.0https://wiki.tiffa.net/w/index.php?title=Translations:Pantothenic_acid/20/en&diff=118146&oldid=prevFuzzyBot: Importing a new version from external source2024-02-20T07:47:09Z<p>Importing a new version from external source</p>
<p><b>New page</b></p><div>==Absorption, metabolism and excretion==<br />
When found in foods, most pantothenic acid is in the form of CoA or bound to [[acyl carrier protein]] (ACP). For the intestinal cells to absorb this vitamin, it must be converted into free pantothenic acid. Within the [[Lumen (anatomy)|lumen]] of the intestine, CoA and ACP are [[Hydrolysis|hydrolyzed]] into 4'-phosphopantetheine. The 4'-phosphopantetheine is then [[Dephosphorylation|dephosphorylated]] into [[pantetheine]]. [[Pantetheine hydrolase|Pantetheinase]], an intestinal enzyme, then hydrolyzes pantetheine into free pantothenic acid. Free pantothenic acid is absorbed into intestinal cells via a saturable, sodium-dependent active transport system. At high levels of intake, when this mechanism is saturated, some pantothenic acid may also be additionally absorbed via passive diffusion. As a whole, when intake increases 10-fold, absorption rate decreases to 10%.</div>FuzzyBot