https://wiki.tiffa.net/w/index.php?action=history&feed=atom&title=Translations%3AObesity%2F58%2FenTranslations:Obesity/58/en - Revision history2026-09-15T05:30:25ZRevision history for this page on the wikiMediaWiki 1.43.0https://wiki.tiffa.net/w/index.php?title=Translations:Obesity/58/en&diff=124611&oldid=prevFuzzyBot: Importing a new version from external source2024-03-05T05:18:27Z<p>Importing a new version from external source</p>
<p><b>New page</b></p><div>The arcuate nucleus contains two distinct groups of [[neuron]]s. The first group coexpresses [[neuropeptide Y]] (NPY) and [[agouti-related peptide]] (AgRP) and has stimulatory inputs to the LH and inhibitory inputs to the VMH. The second group coexpresses [[pro-opiomelanocortin]] (POMC) and [[cocaine- and amphetamine-regulated transcript]] (CART) and has stimulatory inputs to the VMH and inhibitory inputs to the LH. Consequently, NPY/AgRP neurons stimulate feeding and inhibit satiety, while POMC/CART neurons stimulate satiety and inhibit feeding. Both groups of arcuate nucleus neurons are regulated in part by leptin. Leptin inhibits the NPY/AgRP group while stimulating the POMC/CART group. Thus a deficiency in leptin signaling, either via leptin deficiency or leptin resistance, leads to overfeeding and may account for some genetic and acquired forms of obesity.</div>FuzzyBot