https://wiki.tiffa.net/w/index.php?action=history&feed=atom&title=Translations%3ANifedipine%2F1%2Fja 2026-05-31T00:21:55Z Revision history for this page on the wiki MediaWiki 1.43.0 https://wiki.tiffa.net/w/index.php?title=Translations:Nifedipine/1/ja&diff=76440&oldid=prev 2023-11-16T12:04:23Z

<p>Created page with &quot;{{Pathnav|Medication/ja|Antihypertensive drug/ja|Calcium channel blocker/ja|frame=1}} {{Drugbox | verifiedrevid = 462260435 | IUPAC_name = 3,5-dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate | imageL = Nifedipine.svg | imageR = Nifedipine-from-xtal-3D-balls.png | image2 = Nifedipine_substance_photo.jpg &lt;!--Clinical data--&gt; | tradename = Adalat, Procardia, others | Drugs.com = {{drugs.com|monograph|nifedipine}} | MedlinePlus = a684028 | Daily...&quot;</p> <p><b>New page</b></p><div>{{Pathnav|Medication/ja|Antihypertensive drug/ja|Calcium channel blocker/ja|frame=1}}<br /> {{Drugbox<br /> | verifiedrevid = 462260435<br /> | IUPAC_name = 3,5-dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate<br /> | imageL = Nifedipine.svg<br /> | imageR = Nifedipine-from-xtal-3D-balls.png<br /> | image2 = Nifedipine_substance_photo.jpg<br /> &lt;!--Clinical data--&gt;<br /> | tradename = Adalat, Procardia, others<br /> | Drugs.com = {{drugs.com|monograph|nifedipine}}<br /> | MedlinePlus = a684028<br /> | DailyMedID = Nifedipine<br /> | pregnancy_AU = C<br /> | pregnancy_AU_comment = <br /> | pregnancy_category= <br /> | legal_status = <br /> | routes_of_administration = [[Oral administration|By mouth]], topical<br /> | class = [[Calcium channel blocker]] ([[dihydropyridine]])<br /> &lt;!--Pharmacokinetic data--&gt;<br /> | bioavailability = 45-56%<br /> | protein_bound = 92-98%<br /> | metabolism = Gastrointestinal, Liver<br /> | elimination_half-life = 2 hours<br /> | excretion = Kidneys: &gt;50%, Biliary: 5-15%<br /> &lt;!--Identifiers--&gt;<br /> | CAS_number_Ref = {{cascite|correct|??}}<br /> | CAS_number = 21829-25-4<br /> | ATC_prefix = C08<br /> | ATC_suffix = CA05<br /> | ATC_supplemental = <br /> | PubChem = 4485<br /> | IUPHAR_ligand = 2514<br /> | DrugBank_Ref = {{drugbankcite|correct|drugbank}}<br /> | DrugBank = DB01115<br /> | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}<br /> | ChemSpiderID = 4330<br /> | UNII_Ref = {{fdacite|correct|FDA}}<br /> | UNII = I9ZF7L6G2L<br /> | KEGG_Ref = {{keggcite|correct|kegg}}<br /> | KEGG = D00437<br /> | ChEBI_Ref = {{ebicite|correct|EBI}}<br /> | ChEBI = 7565<br /> | ChEMBL_Ref = {{ebicite|correct|EBI}}<br /> | ChEMBL = 193<br /> &lt;!--Chemical data--&gt;<br /> | C=17 | H=18 | N=2 | O=6<br /> | smiles = O=C(OC)\C1=C(\N/C(=C(/C(=O)OC)C1c2ccccc2[N+]([O-])=O)C)C<br /> | StdInChI_Ref = {{stdinchicite|correct|chemspider}}<br /> | StdInChI = 1S/C17H18N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8,15,18H,1-4H3<br /> | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}<br /> | StdInChIKey = HYIMSNHJOBLJNT-UHFFFAOYSA-N<br /> | melting_point = 173<br /> }}<br /> &lt;!-- Definition and medical uses --&gt;<br /> &#039;&#039;&#039;アダラート&#039;&#039;&#039;や&#039;&#039;&#039;プロカルディア&#039;&#039;&#039;などの商品名で販売されている&#039;&#039;&#039;ニフェジピン({{lang-en|Nifedipine}})&#039;&#039;&#039;は、[[angina/ja|狭心症]]、[[hypertension/ja|高血圧]]、[[Raynaud&#039;s phenomenon/ja|レイノー現象]]、[[premature labor/ja|早産]]などの治療に用いられる[[calcium channel blocker/ja|カルシウム拮抗]]医薬品である。[[Prinzmetal angina/ja|プリンツメタル狭心症]]の治療薬のひとつである。[[high blood pressure in pregnancy/ja|妊娠中の重症高血圧]]の治療にも使用されることがある。早産に使用することで、[[corticosteroid/ja|ステロイド]]が赤ちゃんの肺機能を改善する時間を増やし、分娩前に母体を設備の整った医療施設に搬送する時間を確保することができる。[[Dihydropyridine calcium channel blockers/ja|ジヒドロピリジン]]タイプのカルシウム拮抗薬である。ニフェジピンは経口投与で、速放性製剤と徐放性製剤がある。</div>

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