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	<title>Translations:Nicotinamide riboside/8/en - Revision history</title>
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	<updated>2026-05-14T23:15:19Z</updated>
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		<title>FuzzyBot: Importing a new version from external source</title>
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		<updated>2024-04-07T23:19:05Z</updated>

		<summary type="html">&lt;p&gt;Importing a new version from external source&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;In 2004, a previously unknown pathway was reported when nicotinamide riboside (NR) was identified as an additional NAD+ precursor in [[eukaryotes]].&lt;br /&gt;
NR is now recognized as a form of [[Vitamin B3|vitamin B&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;]]  which can be found in both cow and human milk.&lt;br /&gt;
Once internalized into a cell, NR is rapidly phosphorylated by the activity of nicotinamide riboside kinase enzymes (NRK1 and NRK2)  to form nicotinamide mononucleotide (NMN), bypassing the previously known biosynthetic routes to NAD+ production.  NMN is then converted to NAD+ by NMN-adenylyltransferase (NMNAT).&lt;/div&gt;</summary>
		<author><name>FuzzyBot</name></author>
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