https://wiki.tiffa.net/w/index.php?action=history&feed=atom&title=Translations%3ANicotinamide%2F20%2Fen 2026-07-08T16:37:42Z Revision history for this page on the wiki MediaWiki 1.43.0 https://wiki.tiffa.net/w/index.php?title=Translations:Nicotinamide/20/en&diff=133443&oldid=prev 2024-04-03T02:49:04Z

<p>Importing a new version from external source</p> <p><b>New page</b></p><div>=== Biochemistry ===<br /> [[File:NAD+ Oxidation and Reduction.png|thumb|upright=1.3|The active Nicotinamide group on the molecule NAD&lt;sup&gt;+&lt;/sup&gt; undergoes oxidation in many metabolic pathways.]]<br /> Nicotinamide, as a part of the cofactor [[nicotinamide adenine dinucleotide]] (NADH / NAD&lt;sup&gt;+&lt;/sup&gt;) is crucial to life. In cells, nicotinamide is incorporated into NAD&lt;sup&gt;+&lt;/sup&gt; and [[nicotinamide adenine dinucleotide phosphate]] (NADP&lt;sup&gt;+&lt;/sup&gt;). NAD&lt;sup&gt;+&lt;/sup&gt; and NADP&lt;sup&gt;+&lt;/sup&gt; are [[Cofactor (biochemistry)|cofactor]]s in a wide variety of enzymatic [[redox|oxidation-reduction]] reactions, most notably [[glycolysis]], the [[citric acid cycle]], and the [[electron transport chain]]. If humans ingest nicotinamide, it will likely undergo a series of reactions that transform it into NAD, which can then undergo a transformation to form NADP&lt;sup&gt;+&lt;/sup&gt;. This method of creation of NAD&lt;sup&gt;+&lt;/sup&gt; is called a [[Salvage Pathway|salvage pathway]]. However, the human body can produce NAD&lt;sup&gt;+&lt;/sup&gt; from the amino acid [[tryptophan]] and niacin without our ingestion of nicotinamide.</div>

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