https://wiki.tiffa.net/w/index.php?action=history&feed=atom&title=Translations%3ANiacin%2F51%2FenTranslations:Niacin/51/en - Revision history2026-09-20T01:55:29ZRevision history for this page on the wikiMediaWiki 1.43.0https://wiki.tiffa.net/w/index.php?title=Translations:Niacin/51/en&diff=117751&oldid=prevFuzzyBot: Importing a new version from external source2024-02-20T00:42:52Z<p>Importing a new version from external source</p>
<p><b>New page</b></p><div>===Industrial synthesis===<br />
Nicotinic acid was first synthesized in 1867 by oxidative degradation of [[nicotine]] with [[potassium chromate]] and [[sulfuric acid]] — this is the origin of the name. Niacin is prepared by hydrolysis of [[nicotinonitrile]], which, as described above, is generated by oxidation of 3-picoline. Oxidation can be effected by air, but [[ammoxidation]] is more efficient. In the latter process, nicotinonitrile is produced by ammoxidation of [[3-methylpyridine]]. [[Nitrile hydratase]] is then used to catalyze nicotinonitrile to nicotinamide, which can be converted to niacin. Alternatively, ammonia, acetic acid and paraldehyde are used to make [[5-Ethyl-2-methyl-pyridine|5-ethyl-2-methyl-pyridine]], which is then oxidized to niacin. New "greener" catalysts are being tested using manganese-substituted aluminophosphates that use acetyl peroxyborate as non-corrosive oxidant, avoiding producing nitrogen oxides as do traditional ammoxidations.</div>FuzzyBot