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	<title>Translations:Niacin/39/en - Revision history</title>
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	<updated>2026-07-11T18:02:04Z</updated>
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		<title>FuzzyBot: Importing a new version from external source</title>
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		<updated>2024-02-20T00:42:51Z</updated>

		<summary type="html">&lt;p&gt;Importing a new version from external source&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;The acute adverse effects of high-dose niacin therapy ({{nowrap|1–3&amp;amp;nbsp;grams per day}}) &amp;amp;ndash; which is commonly used in the treatment of [[hyperlipidemia]]s &amp;amp;ndash; can further include [[hypotension]], fatigue, [[glucose intolerance]] and [[insulin resistance]], heartburn, blurred or impaired vision, and [[macular edema]]. With long-term use, the adverse effects of high-dose niacin therapy (750&amp;amp;nbsp;mg per day) also include [[liver failure]] (associated with fatigue, nausea, and [[loss of appetite]]), [[hepatitis]], and [[acute liver failure]]; these hepatotoxic effects of niacin occur more often when extended-release [[dosage form]]s are used. The long-term use of niacin at greater than or equal to 2&amp;amp;nbsp;grams per day also significantly increases the [[risk ratio|risk]] of [[cerebral hemorrhage]], [[ischemic stroke]], [[gastrointestinal ulcer]]ation and [[gastrointestinal bleeding|bleeding]], [[diabetes]], [[dyspepsia]], and diarrhea.&lt;/div&gt;</summary>
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