https://wiki.tiffa.net/w/index.php?action=history&feed=atom&title=Translations%3AMetformin%2F50%2FenTranslations:Metformin/50/en - Revision history2026-06-07T09:09:14ZRevision history for this page on the wikiMediaWiki 1.43.0https://wiki.tiffa.net/w/index.php?title=Translations:Metformin/50/en&diff=127364&oldid=prevFuzzyBot: Importing a new version from external source2024-03-11T10:35:33Z<p>Importing a new version from external source</p>
<p><b>New page</b></p><div>== Chemistry ==<br />
Metformin hydrochloride (1,1-dimethylbiguanide hydrochloride) is freely soluble in water, slightly soluble in ethanol, but almost insoluble in acetone, ether, or chloroform. The pK<sub>a</sub> of metformin is 12.4. The usual [[chemical synthesis|synthesis]] of metformin, originally described in 1922, involves the one-pot reaction of [[dimethylamine]] [[hydrochloride]] and [[2-cyanoguanidine]] over heat.</div>FuzzyBot