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	<title>Translations:Metformin/48/en - Revision history</title>
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	<updated>2026-05-11T00:19:44Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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		<title>FuzzyBot: Importing a new version from external source</title>
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		<updated>2024-03-11T10:35:33Z</updated>

		<summary type="html">&lt;p&gt;Importing a new version from external source&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;Metformin is not [[drug metabolism|metabolized]]. It is [[clearance (medicine)|cleared]] from the body by [[renal physiology#Secretion|tubular secretion]] and excreted unchanged in the urine; it is undetectable in blood plasma within 24 hours of a single oral dose. The average [[biological half-life|elimination half-life]] in plasma is 6.2 hours. Metformin is distributed to (and appears to accumulate in) [[red blood cell]]s, with a much longer elimination half-life: 17.6 hours (reported as ranging from 18.5 to 31.5 hours in a single-dose study of nondiabetics).&lt;/div&gt;</summary>
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