https://wiki.tiffa.net/w/index.php?action=history&feed=atom&title=Translations%3AMetformin%2F35%2FenTranslations:Metformin/35/en - Revision history2026-08-15T04:50:29ZRevision history for this page on the wikiMediaWiki 1.43.0https://wiki.tiffa.net/w/index.php?title=Translations:Metformin/35/en&diff=127349&oldid=prevFuzzyBot: Importing a new version from external source2024-03-11T10:35:33Z<p>Importing a new version from external source</p>
<p><b>New page</b></p><div>=== Interactions ===<br />
The [[H2 antagonist|H<sub>2</sub>-receptor antagonist]] [[cimetidine]] causes an increase in the plasma concentration of metformin by reducing [[clearance (medicine)|clearance]] of metformin by the kidneys; both metformin and cimetidine are cleared from the body by [[Renal physiology#Secretion|tubular secretion]], and both, particularly the [[cation]]ic (positively [[electric charge|charged]]) form of cimetidine, may compete for the same transport mechanism. A small [[blind experiment|double-blind]], randomized study found the [[antibiotic]] [[cephalexin]] to also increase metformin concentrations by a similar mechanism; theoretically, other cationic medications may produce the same effect.</div>FuzzyBot