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	<title>Translations:Metabolism/61/en - Revision history</title>
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	<updated>2026-10-25T10:05:23Z</updated>
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		<title>FuzzyBot: Importing a new version from external source</title>
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		<updated>2024-01-22T10:27:09Z</updated>

		<summary type="html">&lt;p&gt;Importing a new version from external source&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;==Evolution==&lt;br /&gt;
{{further|Proto-metabolism|Molecular evolution|Phylogenetics}}&lt;br /&gt;
[[File:Tree of life int.svg|thumb|right|upright=1.8|[[Phylogenetic tree|Evolutionary tree]] showing the common ancestry of organisms from all three [[Domain (biology)|domains]] of life. [[Bacteria]] are colored blue, [[eukaryote]]s red, and [[archaea]] green. Relative positions of some of the [[phylum|phyla]] included are shown around the tree.]]&lt;br /&gt;
The central pathways of metabolism described above, such as glycolysis and the citric acid cycle, are present in all [[Three-domain system|three domains]] of living things and were present in the [[last universal common ancestor]]. This universal ancestral cell was [[prokaryote|prokaryotic]] and probably a [[methanogen]] that had extensive amino acid, nucleotide, carbohydrate and lipid metabolism. The retention of these ancient pathways during later [[evolution]] may be the result of these reactions having been an optimal solution to their particular metabolic problems, with pathways such as glycolysis and the citric acid cycle producing their end products highly efficiently and in a minimal number of steps. The first pathways of enzyme-based metabolism may have been parts of [[purine]] nucleotide metabolism, while previous metabolic pathways were a part of the ancient [[RNA world hypothesis|RNA world]].&lt;/div&gt;</summary>
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