https://wiki.tiffa.net/w/index.php?action=history&feed=atom&title=Translations%3ALosartan%2F27%2FenTranslations:Losartan/27/en - Revision history2026-10-06T21:49:45ZRevision history for this page on the wikiMediaWiki 1.43.0https://wiki.tiffa.net/w/index.php?title=Translations:Losartan/27/en&diff=128822&oldid=prevFuzzyBot: Importing a new version from external source2024-03-14T13:47:09Z<p>Importing a new version from external source</p>
<p><b>New page</b></p><div>Metabolism is primarily by [[cytochrome P450]] [[isoenzyme]]s [[CYP2C9]] and [[CYP3A4]]. Peak plasma concentrations of losartan and EXP3174 occur about one hour and three to four hours, respectively, after an oral dose. Both losartan and EXP3174 are more than 98% bound to plasma proteins. Losartan is excreted in the urine, and in the feces via bile, as unchanged drug and metabolites. About 4% of an oral dose is excreted unchanged in urine, and about 6% is excreted in urine as the active metabolite. The terminal elimination half lives of losartan and EXP3174 are about 1.5 to 2.5 hours and 3 to 9 hours, respectively.</div>FuzzyBot