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<p><b>New page</b></p><div>This basic technique may be enhanced significantly by the use of glucose tracers. Glucose may be labeled with either stable or radioactive atoms. Commonly used tracers are 3-<sup>3</sup>H glucose (radioactive), 6,6 <sup>2</sup>H-glucose (stable) and 1-<sup>13</sup>C Glucose (stable). Prior to beginning the hyperinsulinemic period, a 3h tracer infusion enables one to determine the basal rate of glucose production. During the clamp, the plasma tracer concentrations enable the calculation of whole-body insulin-stimulated glucose metabolism, as well as the production of glucose by the body (i.e., endogenous glucose production).</div>FuzzyBot