https://wiki.tiffa.net/w/index.php?action=history&feed=atom&title=Translations%3AInsulin_analog%2F20%2FenTranslations:Insulin analog/20/en - Revision history2026-09-08T21:13:45ZRevision history for this page on the wikiMediaWiki 1.43.0https://wiki.tiffa.net/w/index.php?title=Translations:Insulin_analog/20/en&diff=130156&oldid=prevFuzzyBot: Importing a new version from external source2024-03-19T08:49:44Z<p>Importing a new version from external source</p>
<p><b>New page</b></p><div>==Timeline==<br />
* 1922 Banting and Best use bovine insulin extract on human<br />
* 1923 [[Eli Lilly and Company]] (Lilly) produces commercial quantities of bovine insulin<br />
* 1923 Hagedorn founds the Nordisk Insulinlaboratorium in Denmark forerunner of [[Novo Nordisk]]<br />
* 1926 [[Novo Nordisk|Nordisk]] receives Danish charter to produce insulin as a non-profit<br />
* 1936 Canadians D.M. Scott and A.M. Fisher formulate zinc insulin mixture and license to Novo<br />
* 1936 Hagedorn discovers that adding protamine to insulin prolongs the effect of insulin<br />
* 1946 Nordisk formulates Isophane porcine insulin a.k.a. Neutral Protamine Hagedorn or [[NPH insulin]]<br />
* 1946 Nordisk crystallizes a protamine and insulin mixture<br />
* 1950 Nordisk markets NPH insulin<br />
* 1953 Novo formulates Lente porcine and bovine insulins by adding zinc for longer-lasting insulin<br />
* 1978 [[Genentech]] develop biosynthesis of recombinant human insulin in ''Escherichia coli'' bacteria using recombinant DNA technology<br />
* 1981 Novo Nordisk chemically and enzymatically converts porcine insulin to 'human' insulin (Actrapid HM)<br />
* 1982 [[Genentech]] synthetic 'human' insulin approved, in partnership with Eli Lilly and Company, who shepherded the product through the U.S. [[Food and Drug Administration]] (FDA) approval process<br />
* 1983 Lilly produces biosynthetic recombinant "rDNA insulin human INN" (Humulin)<br />
* 1985 [[Axel Ullrich]] sequences the human insulin receptor<br />
* 1988 Novo Nordisk produces synthetic, recombinant insulin ("insulin human INN")<br />
* 1996 Lilly Humalog "insulin lispro INN" approved by the U.S. Food and Drug Administration<br />
* 2003 [[Aventis]] Lantus "glargine" insulin analogue approved in USA <br />
* 2004 [[Sanofi Aventis]] Apidra insulin "glulisine" analogue approved in the USA.<br />
* 2006 Novo Nordisk's Levemir "insulin detemir INN" analogue approved in the USA-<br />
* 2013 Novo Nordisk's Tresiba "insulin degludec INN" analogue approved in Europe (EMA with additional monitoring]</div>FuzzyBot