https://wiki.tiffa.net/w/index.php?action=history&feed=atom&title=Translations%3AInsulin_%28medication%29%2F26%2FenTranslations:Insulin (medication)/26/en - Revision history2026-08-15T03:12:39ZRevision history for this page on the wikiMediaWiki 1.43.0https://wiki.tiffa.net/w/index.php?title=Translations:Insulin_(medication)/26/en&diff=130651&oldid=prevFuzzyBot: Importing a new version from external source2024-03-21T04:16:39Z<p>Importing a new version from external source</p>
<p><b>New page</b></p><div>== Challenges in treatment ==<br />
There are several challenges involved in the use of insulin as a clinical treatment for diabetes:<br />
* Mode of administration.<br />
* Selecting the 'right' dose and timing. The amount of carbohydrates one unit of insulin handles varies widely between persons and over the day but values between 7 and 20 grams per 1 IE is typical.<br />
* Selecting an appropriate insulin preparation (typically on 'speed of onset and duration of action' grounds).<br />
* Adjusting dosage and timing to fit food intake timing, amounts, and types.<br />
* Adjusting dosage and timing to fit exercise undertaken.<br />
* Adjusting dosage, type, and timing to fit other conditions, for instance the increased stress of illness.<br />
* Variability in absorption into the bloodstream via subcutaneous delivery<br />
* The dosage is non-physiological in that a subcutaneous [[Bolus (medicine)|bolus]] dose of insulin alone is administered instead of combination of insulin and [[C-peptide]] being released gradually and directly into the [[portal vein]].<br />
* It is simply a nuisance for people to inject whenever they eat carbohydrate or have a high blood glucose reading.<br />
* It is dangerous in case of mistake (such as 'too much' insulin).</div>FuzzyBot