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	<title>Translations:Hyperuricemia/26/en - Revision history</title>
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	<updated>2026-08-15T05:02:55Z</updated>
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		<title>FuzzyBot: Importing a new version from external source</title>
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		<updated>2024-04-22T09:17:53Z</updated>

		<summary type="html">&lt;p&gt;Importing a new version from external source&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;Some of these medications are used as [[Indication (medicine)|indicated]], others are used [[Off-label use|off-label]]. In people receiving [[hemodialysis]], [[sevelamer]] can significantly reduce serum uric acid, apparently by adsorbing urate in the gut. In women, use of [[combined oral contraceptive pill]]s is significantly associated with lower serum uric acid. Following [[Le Chatelier&amp;#039;s principle]], lowering the blood concentration of uric acid may permit any existing crystals of uric acid to gradually dissolve into the blood, whence the dissolved uric acid can be excreted. Maintaining a lower blood concentration of uric acid similarly should reduce the formation of new crystals. If the person has chronic [[gout]] or known [[Tophus|tophi]], then large quantities of uric acid crystals may have accumulated in joints and other tissues, and aggressive and/or long duration use of medications may be needed. Precipitation of uric acid crystals, and conversely their dissolution, is known to be dependent on the concentration of uric acid in solution, [[pH]], sodium concentration, and temperature.&lt;/div&gt;</summary>
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