https://wiki.tiffa.net/w/index.php?action=history&feed=atom&title=Translations%3AHypertension%2F76%2FenTranslations:Hypertension/76/en - Revision history2026-07-09T11:47:20ZRevision history for this page on the wikiMediaWiki 1.43.0https://wiki.tiffa.net/w/index.php?title=Translations:Hypertension/76/en&diff=123520&oldid=prevFuzzyBot: Importing a new version from external source2024-02-29T13:03:02Z<p>Importing a new version from external source</p>
<p><b>New page</b></p><div>The first chemical for hypertension, [[sodium thiocyanate]], was used in 1900 but had many side effects and was unpopular. Several other agents were developed after the [[World War II|Second World War]], the most popular and reasonably effective of which were [[tetramethylammonium chloride]], [[hexamethonium]], [[hydralazine]], and [[reserpine]] (derived from the medicinal plant ''[[Rauvolfia serpentina]]''). None of these were well tolerated. A major breakthrough was achieved with the discovery of the first well-tolerated orally available agents. The first was [[chlorothiazide]], the first [[thiazide]] [[diuretic]] and developed from the antibiotic [[sulfanilamide]], which became available in 1958. Subsequently, [[beta blocker]]s, [[calcium channel blockers]], [[angiotensin converting enzyme]] (ACE) inhibitors, [[angiotensin receptor blockers]], and [[renin inhibitors]] were developed as antihypertensive agents.</div>FuzzyBot