https://wiki.tiffa.net/w/index.php?action=history&feed=atom&title=Translations%3AHydroxocobalamin%2F13%2FenTranslations:Hydroxocobalamin/13/en - Revision history2026-05-14T10:14:05ZRevision history for this page on the wikiMediaWiki 1.43.0https://wiki.tiffa.net/w/index.php?title=Translations:Hydroxocobalamin/13/en&diff=136165&oldid=prevFuzzyBot: Importing a new version from external source2024-04-07T01:35:05Z<p>Importing a new version from external source</p>
<p><b>New page</b></p><div>===Injectable hydroxocobalamin===<br />
Injection of hydroxocobalamin is used to rectify the following causes of vitamin B<sub>12</sub> deficiency (list taken from the drug prescription label published by the [[Food and Drug Administration (United States)|U.S. Food and Drug Administration]])<br />
* Dietary deficiency of vitamin B<sub>12</sub> occurring in strict vegetarians and in their [[breastfed]] infants (isolated vitamin B<sub>12</sub> deficiency is very rare)<br />
* Malabsorption of vitamin B<sub>12</sub> resulting from damage to the stomach, where [[intrinsic factor]] is secreted, or damage to the [[ileum]], where intrinsic factor facilitates vitamin B<sub>12</sub> absorption. These conditions include [[tropical sprue]] and [[nontropical sprue]] (celiac disease).<br />
* Inadequate secretion of intrinsic factor, resulting from lesions that destroy the [[gastric mucosa]] (which can be caused by ingestion of corrosives, extensive [[tumors]], and conditions associated with gastric atrophy, such as [[multiple sclerosis]], certain [[endocrine disorders]], [[Iron deficiency (medicine)|iron deficiency]], and subtotal [[gastrectomy]])<br />
* Structural lesions leading to vitamin B<sub>12</sub> deficiency, including regional [[ileitis]], ileal reactions, and malignancies<br />
* Competition for vitamin B<sub>12</sub> by [[intestinal parasites]] or bacteria. The [[tapeworm]] from undercooked fish (''[[Diphyllobothrium latum]]'') absorbs huge quantities of vitamin B<sub>12</sub>, and infested patients often have associated gastric atrophy. The [[blind loop syndrome]] may produce deficiency of vitamin B<sub>12</sub> or [[folate]].<br />
* Inadequate use of vitamin B<sub>12</sub>, which may occur if [[antimetabolites]] for the vitamin are employed in the treatment of [[neoplasia]]<br />
[[Pernicious anemia]] is the most common cause of vitamin B<sub>12</sub> deficiency. While it technically refers to anemia caused specifically by autoimmune deficiency of intrinsic factor, it is commonly used to refer to B<sub>12</sub>-deficient anemia as a whole, regardless of cause.</div>FuzzyBot