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	<title>Translations:Glucagon-like peptide-1/6/en - Revision history</title>
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	<updated>2026-08-18T06:16:08Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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		<title>FuzzyBot: Importing a new version from external source</title>
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		<updated>2024-03-11T00:48:14Z</updated>

		<summary type="html">&lt;p&gt;Importing a new version from external source&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;The proglucagon gene is expressed in several organs including the [[pancreas]] ([[α-cell]]s of the [[islets of Langerhans]]), gut (intestinal enteroendocrine L-cells) and [[brain]] (caudal [[brainstem]] and [[hypothalamus]]). Pancreatic proglucagon gene expression is promoted upon fasting and hypoglycaemia induction and inhibited by insulin. Conversely, intestinal proglucagon gene expression is reduced during fasting and stimulated upon food consumption. In mammals, the transcription gives rise to identical [[mRNA]] in all three cell types, which is further translated to the 180 amino acid precursor called [[proglucagon]]. However, as a result of tissue-specific posttranslational processing mechanisms, different peptides are produced in the different cells.&lt;/div&gt;</summary>
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