https://wiki.tiffa.net/w/index.php?action=history&feed=atom&title=Translations%3AGlucagon-like_peptide-1%2F4%2FenTranslations:Glucagon-like peptide-1/4/en - Revision history2026-07-13T22:53:13ZRevision history for this page on the wikiMediaWiki 1.43.0https://wiki.tiffa.net/w/index.php?title=Translations:Glucagon-like_peptide-1/4/en&diff=127231&oldid=prevFuzzyBot: Importing a new version from external source2024-03-11T00:48:14Z<p>Importing a new version from external source</p>
<p><b>New page</b></p><div>Endogenous GLP-1 is rapidly degraded primarily by [[dipeptidyl peptidase-4]] (DPP-4), as well as neutral endopeptidase 24.11 (NEP 24.11) and [[renal clearance]], resulting in a [[half-life]] of approximately 2 minutes. Consequently, only 10–15 % of GLP-1 reaches circulation intact, leading to fasting plasma levels of only 0–15 pmol/L. To overcome this, [[GLP-1 receptor agonist]]s and [[DPP-4 inhibitors]] have been developed to increase GLP-1 activity. As opposed to common treatment agents such as [[insulin]] and [[sulphonylurea]], GLP-1-based treatment has been associated with [[weight loss]] and a lower risk of [[hypoglycemia]], two important considerations for patients with type 2 diabetes.</div>FuzzyBot