https://wiki.tiffa.net/w/index.php?action=history&feed=atom&title=Translations%3AGlucagon-like_peptide-1%2F2%2Fen 2026-11-11T15:56:02Z Revision history for this page on the wiki MediaWiki 1.43.0 https://wiki.tiffa.net/w/index.php?title=Translations:Glucagon-like_peptide-1/2/en&diff=127229&oldid=prev 2024-03-11T00:48:14Z

<p>Importing a new version from external source</p> <p><b>New page</b></p><div>&#039;&#039;&#039;Glucagon-like peptide-1&#039;&#039;&#039; (&#039;&#039;&#039;GLP-1&#039;&#039;&#039;) is a 30- or 31-amino-acid-long [[peptide hormone]] deriving from the tissue-specific posttranslational processing of the [[proglucagon]] peptide. It is produced and secreted by intestinal [[Enteroendocrine cell|enteroendocrine L-cells]] and certain neurons within the [[Solitary nucleus|nucleus of the solitary tract]] in the brainstem upon food consumption. The initial product GLP-1 (1–37) is susceptible to [[amidation]] and [[proteolytic cleavage]], which gives rise to the two truncated and equipotent biologically active forms, GLP-1 (7–36) amide and GLP-1 (7–37). Active GLP-1 [[protein secondary structure]] includes two [[α-helices]] from amino acid position 13–20 and 24–35 separated by a linker region.</div>

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