https://wiki.tiffa.net/w/index.php?action=history&feed=atom&title=Translations%3AFolate%2F31%2FenTranslations:Folate/31/en - Revision history2026-04-16T19:41:23ZRevision history for this page on the wikiMediaWiki 1.43.0https://wiki.tiffa.net/w/index.php?title=Translations:Folate/31/en&diff=134743&oldid=prevFuzzyBot: Importing a new version from external source2024-04-05T04:48:09Z<p>Importing a new version from external source</p>
<p><b>New page</b></p><div>=== Bioactivation ===<br />
[[File:Folic Acid Biotransformations.svg|thumb|400px|Biotransformation of folic acid into [[folinic acid]]s where R = para-aminobenzoate-glutamate]]<br />
All of the biological functions of folic acid are performed by [[tetrahydrofolate|THF]] and its [[methylated]] derivatives. Hence folic acid must first be [[redox|reduced]] to THF. This four electron reduction proceeds in two chemical steps both catalyzed by the same enzyme, [[dihydrofolate reductase]]. Folic acid is first reduced to [[dihydrofolate]] and then to tetrahydrofolate. Each step consumes one molecule of [[NADPH]] ([[biosynthesis|biosynthetically]] derived from [[Niacin (nutrient)|vitamin B<sub>3</sub>]]) and produces one molecule of [[NADP]].</div>FuzzyBot