https://wiki.tiffa.net/w/index.php?action=history&feed=atom&title=Translations%3AFlavin_adenine_dinucleotide%2F43%2Fen Translations:Flavin adenine dinucleotide/43/en - Revision history 2026-09-14T01:59:52Z Revision history for this page on the wiki MediaWiki 1.43.0 https://wiki.tiffa.net/w/index.php?title=Translations:Flavin_adenine_dinucleotide/43/en&diff=136822&oldid=prev FuzzyBot: Importing a new version from external source 2024-04-10T10:54:11Z <p>Importing a new version from external source</p> <p><b>New page</b></p><div>&#039;&#039;p&#039;&#039;-Hydroxybenzoate hydroxylase (PHBH) catalyzes the oxygenation of &#039;&#039;p&#039;&#039;-hydroxybenzoate (&#039;&#039;p&#039;&#039;OHB) to 3,4-dihyroxybenzoate (3,4-diOHB); FAD, NADPH and molecular oxygen are all required for this reaction. NADPH first transfers a hydride equivalent to FAD, creating FADH&lt;sup&gt;−&lt;/sup&gt;, and then NADP&lt;sup&gt;+&lt;/sup&gt; dissociates from the enzyme. Reduced PHBH then reacts with molecular oxygen to form the flavin-C(4a)-hydroperoxide. The flavin hydroperoxide quickly hydroxylates &#039;&#039;p&#039;&#039;OHB, and then eliminates water to regenerate oxidized flavin. An alternative flavin-mediated oxygenation mechanism involves the use of a [[Amine oxide|flavin-N(5)-oxide]] rather than a flavin-C(4a)-(hydro)peroxide.</div> FuzzyBot